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Katarzyna (Kasia) Sidorczuk

Academic CV and research profile of Katarzyna (Kasia) Sidorczuk, a BioGenies collaborator.

Biography

Hi! My name is Katarzyna Sidorczuk and I’m a bioinformatician interested in gut microbiome and use of machine learning for analysis of biological data.

During my PhD I worked with BioGenies and created multiple tools for prediction of peptide activity and protein localization. This led us to the work on negative data sampling for AMP prediction in which we showed that commonly used strategies introduce significance bias and leads to unreliable benchmarks.

Currently, I’m a postdoc in the Hildebrand group at the Quadram Institute, where I work with strain-resolved metagenomics. I’m interested in evolution of gut microbiota, how microbes are transferred between family members, and what are the factors that contribute to successful colonization and persistence.

Contact

Email GitHub ORCID

Conferences, workshops and training

13 conference and training events

Polish Bioinformatics Society (PTBI) logo

2024-09-11 – 2024-09-13

Symposium of the Polish Bioinformatics Society

Warsaw, Poland
Talks, posters & participation (1)
  • Talk

    Strain-resolved metagenomics in analysis of gut microbiota dynamics within families

ECCB

2022-09-18 – 2022-09-21

European Conference on Computational Biology

Sitges, Spain
Talks, posters & participation (1)
  • Where do they come from, where do they go? Prediction of protein subplastid localization and origin with PlastoGram

ESCS

2022-09-18

European Student Council Symposium

Sitges, Spain
Talks, posters & participation (1)
  • Where do they come from, where do they go? Prediction of protein subplastid localization and origin with PlastoGram

Earlier activities (10)
2022 1
GCB

2022-09-06 – 2022-09-08

German Conference on Bioinformatics

Halle (Salle), Germany
Talks, posters & participation (1)
  • Where do they come from, where do they go? PlastoGram: a stacked model for prediction of protein subplastid localization and origin

2021 1
EYSF

2021-10-21 – 2021-10-22

EMBO Young Scientists' Forum (EYSF)

Warsaw, Poland
Talks, posters & participation (1)
  • Poster

    CancerGram: How to differentiate anticancer from antimicrobial peptides?

2020 2
IBID

2020-10-28 – 2020-10-29

International Biotech Innovation Days

Senftenberg, Germany
Talks, posters & participation (1)
  • Poster

    Prediction of antimicrobial peptides with AmpGram

DSS

2020-10-16

Data Science Summit

Warsaw, Poland
Talks, posters & participation (1)
  • Reproducible analytic workflows in R with drake and renv

2019 3
Why R? conference series logo

2019-09-26 – 2019-09-29

Why R? Conference

Warszawa, Poland
Talks, posters & participation (1)
  • Talk

    PepBay: Implementation of Bayesian inference in the analysis of peptide arrays

Polish Bioinformatics Society (PTBI) logo

2019-09-19 – 2019-09-21

Symposium of the Polish Bioinformatics Society

Cracow, Poland
Talks, posters & participation (1)
  • In silico identification and phylogeny of components responsible for protein import into thylakoids of Paulinella photosynthetic species

SatRday

2019-05-17 – 2019-05-18

Conference for users of the R Language

Gdańsk, Poland
Talks, posters & participation (1)
  • Talk

    Bayesian inference in big data analysis

2018 3
PL in ML

2018-12-14 – 2018-12-17

Polish View on Machine Learning

Warsaw, Poland
Talks, posters & participation (1)
  • Poster

    PepBay: a Bayesian framework for analysis of peptide arrays

Polish Bioinformatics Society (PTBI) logo

2018-09-05 – 2018-09-07

Symposium of the Polish Bioinformatics Society

Wrocław, Poland
Talks, posters & participation (1)
  • Poster

    Two protein import pathways into the cyanobacteria-derived, photosynthetic organelles of Paulinella chromatophora

IBID

2018-05-23 – 2018-05-25

International Biotech Innovation Days

Senftenberg, Germany
Talks, posters & participation (1)
  • Poster

    Protein import into the chromatophores of Paulinella photosynthetic species

Publications

29 publications listed · most recent first

Temporal strain-resolved metagenomics associates IBD dysbiosis with gastrointestinal inflammation

Nature Communications · 2026-10-21

Authors & citation details

Rebecca Ansorge, Stefano Romano, Clémence Frioux, Tamas Douglas Korcsmaros, Nathalie Juge, Katarzyna Sidorczuk, Falk Hildebrand

Authorship: coauthor

https://doi.org/10.1038/s41467-026-78621-7
Effect of dietary chickpea structures on the small intestine metabolome and microbiome: a randomised crossover trial

Nature Communications · 2026-09-15

Authors & citation details

Nadia J. Fernandes, Mingzhu Cai, Frederick J. Warren, Anthony Duncan, José Iván Serrano-Contreras, Katarzyna Sidorczuk, Andrés Bernal, Andrés Bernal, Katerina Petropoulou, Natalia Pérez‐Moral, Isabel García‐Pérez, Cathrina H. Edwards, Elaine C. Holmes, Julien Wist, Gary Steven Frost

Authorship: coauthor

https://doi.org/10.1038/s41467-026-77714-7
Diet-Metabolomics-Microbiome Pipeline for "Dietary Modulation of The Human Small Intestine Metabolome and Microbiome" Study

Code Ocean · 2026-08-12

Authors & citation details

Nadia J. Fernandes, Mingzhu Cai, Frederick J. Warren, José Iván Serrano-Contreras, Katarzyna Sidorczuk, Andres Bernal, Katerina Petropoulou, Dominic M Blunt, Natalia Pérez‐Moral, Isabel García‐Pérez, Falk Hildebrand, Elaine C. Holmes

Authorship: coauthor

https://doi.org/10.24433/co.3003445.v1
Earlier publications (26)
2026 4
Supplementation with effective microorganisms in earthen ponds affects common carp growth and abundance of specific bacterial families

BMC Genomics · 2026-06-23

Authors & citation details

Michalina Jakimowicz, Katarzyna Sidorczuk, David C. Huyben, Falk Hildebrand, Łukasz Napora-Rutkowski, Piotr Hajduk, Marek Sztuka, Magda Mielczarek, Magda Mielczarek, Dawid Słomian, Laura Jarosz, Joanna Szyda

Authorship: coauthor

https://doi.org/10.1186/s12864-026-13093-z
Copper is an intestinal habitat filter affecting the gut microbiota interactions with Salmonella Typhimurium

Microbiome · 2026-03-28

Authors & citation details

Rafał Kolenda, Marwa M. Hassan, Ainhoa Arrieta-Gisasola, Rebecca Ansorge, Katarzyna Sidorczuk, Luke Acton, Gaetan J. A. Thilliez, Dave Baker, Michał Jan Burdukiewicz, Mark D. Stares, Hilary P. Browne, Gwénaëlle Le Gall, Mark P. Stevens, Trevor D. Lawley, Andreas J. Bäumler, Roberto La Ragione, Falk Hildebrand, Robert A. Kingsley

Authorship: coauthor

https://doi.org/10.1186/s40168-025-02322-4
Additional file 3 of Copper is an intestinal habitat filter affecting the gut microbiota interactions with Salmonella Typhimurium

Figshare · 2026-03-28

Authors & citation details

Rafał Kolenda, Marwa M. Hassan, Ainhoa Arrieta-Gisasola, Rebecca Ansorge, Katarzyna Sidorczuk, Luke Acton, Gaetan J. A. Thilliez, Dave Baker, Michał Jan Burdukiewicz, Mark D. Stares, Hilary P. Browne, Gwenaelle Le Gall, Mark P. Stevens, Trevor D. Lawley, Andreas J. Bäumler, Roberto La Ragione, Falk Hildebrand, Robert A. Kingsley

Authorship: coauthor

https://doi.org/10.6084/m9.figshare.31969200
Deep Learning and feature selection in the bioinformatic modelling of functionally annotated microbial communities in aquaculture

World Congress on Genetics Applied to Livestock Production (WCGALP) · 2026-02-26

Authors & citation details

Joanna Szyda, Marek Sztuka, Michalina Jakimowicz, Katarzyna Sidorczuk, Dawid Słomian, Łukasz Napora-Rutkowski

Authorship: coauthor

https://doi.org/10.31274/wcgalp.23784
2025 7
Bioinformatics Processing of Whole Metagenome Shotgun Datasets

Springer protocols handbooks/Springer protocols · 2025-12-04

Authors & citation details

Wing Koon, Katarzyna Sidorczuk, Alise Jany Ponsero, Sumeet K. Tiwari, Falk Hildebrand, Andrea Telatin

Authorship: coauthor

https://doi.org/10.1007/978-1-0716-5009-7_11
Bioinformatics Processing of 16S Datasets

Springer protocols handbooks/Springer protocols · 2025-12-04

Authors & citation details

Alise Jany Ponsero, Judit Tálas, Katarzyna Sidorczuk, Wing Koon, Falk Hildebrand, Andrea Telatin

Authorship: coauthor

https://doi.org/10.1007/978-1-0716-5009-7_10
Dietary Modulation of The Human Small Intestine Metabolome and Microbiome

medRxiv · 2025-11-27

Authors & citation details

Nadia J. Fernandes, Mingzhu Cai, Frederick J. Warren, Anthony Duncan, Hannah C. Harris, Katarzyna Sidorczuk, Andrés Bernal, Katerina Petropoulou, Dominic M Blunt, Natalia Pérez‐Moral, Isabel García‐Pérez, Cathrina H. Edwards, Falk Hildebrand, Elaine C. Holmes, Julien Wist, Gary Steven Frost

Authorship: coauthor

https://doi.org/10.1101/2025.11.25.25340785
Detecting signatures underlying the composition of biological data

Nucleic Acids Research · 2025-11-22

Authors & citation details

Anthony Duncan, Wing Koon, Katarzyna Sidorczuk, Christopher Quince, Clémence Frioux, Falk Hildebrand

Authorship: coauthor

https://doi.org/10.1093/nar/gkaf1388
Dating the Origin and Spread of Plastids and Chromatophores

International Journal of Molecular Sciences · 2025-06-11

Authors & citation details

Filip Pietluch, Paweł Mackiewicz, Katarzyna Sidorczuk, Przemysław Gagat

Authorship: coauthor

https://doi.org/10.3390/ijms26125569
1284: SPATIOTEMPORAL PROFILING OF THE HUMAN SMALL INTESTINAL MICROBIOME

Gastroenterology · 2025-05-01

Authors & citation details

Frederick J. Warren, Nadia J. Fernandes, Katarzyna Sidorczuk, Katerina Petropoulou, Hannah C. Harris, Isabel García‐Pérez, Falk Hildebrand, Gary Steven Frost

Authorship: coauthor

https://doi.org/10.1016/s0016-5085(25)01662-2
Supplementation with Effective Microorganisms in Earthen Ponds Affects Common Carp Growth But Not Overall Microbial Communities

bioRxiv (Cold Spring Harbor Laboratory) · 2025-01-01

Authors & citation details

Michalina Jakimowicz, Katarzyna Sidorczuk, David C. Huyben, Falk Hildebrand, Łukasz Napora-Rutkowski, Marek Sztuka, Magda Mielczarek, Magda Mielczarek, Dawid Słomian, Joanna Szyda

Authorship: coauthor

https://doi.org/10.1101/2025.07.07.663436
2024 2
adhesiomeR: a tool for Escherichia coli adhesin classification and analysis

BMC Genomics · 2024-06-17

Authors & citation details

Katarzyna Sidorczuk, Michał Jan Burdukiewicz, Joachim Fritscher, Robert A. Kingsley, Peter Schierack, Falk Hildebrand, Rafał Kolenda

Authorship: first

https://doi.org/10.1186/s12864-024-10525-6
Characterization of clumpy adhesion of Escherichia coli to human cells and associated factors influencing antibiotic sensitivity

Microbiology Spectrum · 2024-03-26

Authors & citation details

Muhammad Moman Khan, Katarzyna Sidorczuk, Adrianna Aleksandrowicz, Christina Ludwig, Aamir Ali, Robert A. Kingsley, Peter Schierack, Rafał Kolenda

Authorship: coauthor

https://doi.org/10.1128/spectrum.02606-23
2023 4
Why IBD is so hard to treat – and how scientists are making progress

2023-12-21

Authors & citation details

Falk Hildebrand, Katarzyna Sidorczuk, Wing Koon

Authorship: coauthor

https://doi.org/10.64628/ab.64f65khy6
Characterization of signal and transit peptides based on motif composition and taxon-specific patterns

Scientific Reports · 2023-09-21

Authors & citation details

Katarzyna Sidorczuk, Paweł Mackiewicz, Filip Pietluch, Przemysław Gagat

Authorship: first

https://doi.org/10.1038/s41598-023-42987-1
Prediction of protein subplastid localization and origin with PlastoGram

Scientific Reports · 2023-05-24

Authors & citation details

Katarzyna Sidorczuk, Przemysław Gagat, Jakub Kała, Henrik Nielsen, Filip Pietluch, Paweł Mackiewicz, Michał Jan Burdukiewicz

Authorship: first

https://doi.org/10.1038/s41598-023-35296-0
Genomic characterization of enterohaemolysin-encoding haemolytic Escherichia coli of animal and human origin

Microbial Genomics · 2023-04-27

Authors & citation details

Katarzyna Sidorczuk, Adrianna Aleksandrowicz, Michał Jan Burdukiewicz, Robert A. Kingsley, Rafał Kolenda

Authorship: first

https://doi.org/10.1099/mgen.0.000999
2022 2
Benchmarks in antimicrobial peptide prediction are biased due to the selection of negative data

Briefings in Bioinformatics · 2022-08-21

Authors & citation details

Katarzyna Sidorczuk, Przemysław Gagat, Filip Pietluch, Jakub Kała, Dominik Rafacz, Laura Bąkała, Jadwiga Słowik, Rafał Kolenda, Stefan Rödiger, Legana C H W Fingerhut, Ira Cooke, Paweł Mackiewicz, Michał Jan Burdukiewicz

Authorship: first

https://doi.org/10.1093/bib/bbac343
The dynamic landscape of peptide activity prediction

Computational and Structural Biotechnology Journal · 2022-01-01

Authors & citation details

Oriol Bárcenas, Carlos Pintado‐Grima, Katarzyna Sidorczuk, Felix Teufel, Henrik Nielsen, Salvador Ventura, Michał Jan Burdukiewicz

Authorship: coauthor

https://doi.org/10.1016/j.csbj.2022.11.043
2021 3
Genome placement of alpha-haemolysin cluster is associated with alpha-haemolysin sequence variation, adhesin and iron acquisition factor profile of Escherichia coli

Microbial Genomics · 2021-12-23

Authors & citation details

Rafał Kolenda, Katarzyna Sidorczuk, Mateusz Noszka, Adrianna Aleksandrowicz, Muhammad Moman Khan, Michał Jan Burdukiewicz, Peter Schierack

Authorship: coauthor

https://doi.org/10.1099/mgen.0.000743
Whatever makes them stick – Adhesins of avian pathogenic Escherichia coli

Veterinary Microbiology · 2021-04-24

Authors & citation details

Adrianna Aleksandrowicz, Muhammad Moman Khan, Katarzyna Sidorczuk, Mateusz Noszka, Rafał Kolenda

Authorship: coauthor

https://doi.org/10.1016/j.vetmic.2021.109095
Correction to: The Photosynthetic Adventure of Paulinella Spp

Results and problems in cell differentiation · 2021-01-01

Authors & citation details

Przemysław Gagat, Katarzyna Sidorczuk, Filip Pietluch, Paweł Mackiewicz

Authorship: coauthor

https://doi.org/10.1007/978-3-030-51849-3_24
2020 3
CancerGram: An Effective Classifier for Differentiating Anticancer from Antimicrobial Peptides

Pharmaceutics · 2020-10-31

Authors & citation details

Michał Jan Burdukiewicz, Katarzyna Sidorczuk, Dominik Rafacz, Filip Pietluch, Laura Bąkała, Jadwiga Słowik, Przemysław Gagat

Authorship: coauthor

https://doi.org/10.3390/pharmaceutics12111045
Proteomic Screening for Prediction and Design of Antimicrobial Peptides with AmpGram

International Journal of Molecular Sciences · 2020-06-17

Authors & citation details

Michał Jan Burdukiewicz, Katarzyna Sidorczuk, Dominik Rafacz, Filip Pietluch, Jarosław Chilimoniuk, Stefan Rödiger, Przemysław Gagat

Authorship: coauthor

https://doi.org/10.3390/ijms21124310
The Photosynthetic Adventure of Paulinella Spp

Results and problems in cell differentiation · 2020-01-01

Authors & citation details

Przemysław Gagat, Katarzyna Sidorczuk, Filip Pietluch, Paweł Mackiewicz

Authorship: coauthor

https://doi.org/10.1007/978-3-030-51849-3_13
2018 1
Paulinella chromatophora – niezwykła fotosyntetyczna przygoda ameby i sinicy

Kosmos · 2018-10-25

Authors & citation details

Katarzyna Sidorczuk, Paweł Mackiewicz, Przemysław Gagat

Authorship: first

https://doi.org/10.36921/kos.2018_2455

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